为了加强与母校的科研合作和学术交流，我海外校友、化学学院兼职教授、美国纽约州立大学（The State University of New York at Buffalo）龚兵教授应邀于2006年6月29日来我院作了Self-Assembling and Folding Nanoporous Structures 精彩的学术报告。 龚教授重点讲授含有纳米孔径、内径可调的螺旋折叠超分子和大环超分子的设计与合成，以及大环超分子在细胞膜上通过自组装形成离子及分子通道等国外的最新研究。 他生动有趣的讲座，使广大师生受益匪浅。 学术报告后，龚教授就进一步加强与母校的科研合作与学术交流，交换了意见，并对母校的110周年华诞及学院的99岁生日表示衷心地祝贺，他祝愿母校明天更美好！ 龚兵教授简历1980-1984 四川大学 本科 获学士学位1985-1990 美国芝加哥大学 博士 获博士学位1991,1-1994,7 美国加利福尼亚大学伯克利分校 博士后1994,9-1996,5 美国俄亥俄大学 助理教授1996,6-2000,5 美国Toledo大学 助理教授, 副教授2000,6-2004 美国纽约州立大学布法罗分校 副教授2004--今 美国布法罗纽约州立大学 教授2003--今 北京师范大学兼职教授 博导2006--今 四川大学兼职教授主要学术兼职2005- 中国教育部重要人才计划讲座教授2004- 国家自然科学进步奖海外评审专家2002- 美国国家卫生研究院（NIH)医学化学部评审委员会委员2001- 美国国家卫生研究院 (NIH)生物有机和天然产物部评审委员会委员1999- 美国化学会,美国能源部,美国国家自然科学基金委员会及香港的大学教育金委员会评委1996- J.Am.Chem.Soc., Chem.Commun., Chem.Mater., Org.Lett, Supra. Mol. Chem., & Bioorg. Med. Chem. Lett.和J.Org.Chem. 等杂志审稿人 龚兵教授先后和正在主持美国NIH（美国国立卫生研究院）、NSF（美国国家基金）、NASA(美国航空航天局)、ONR（美国海军）等多个美国国家研究基金会的项目。多年来一直从事超分子材料的研究，在超分子领域的分子识别、自组装及非天然折叠大分子领域首次设计并成功构建了一类全新的具有顺序特异可编控和稳定性可调的双分子链，已被成功用作诱发蛋白质二级结构的模板，以及新颖的超分子嵌段共聚物和其它各类纳米结构的设计。这一成果首次统一了非共价键系统的高度专一性与共价键系统的高度稳定性，为在温和（生理）条件下制备新型的“聪明”生物材料，提供了现实可能性。此外，成功地设计并获得了含有纳米孔径、内径可调的螺旋折叠分子及疏水和亲水纳米管。最新的结果表明，这一类具有纳米孔径的分子可作为高效的离子及分子通道，选择性的作用于特定细胞，在细胞上开孔，使细胞雕亡；近年合成了系列含亲水纳米孔径的刚性大环，正在进行的生物物理研究表明这些大环在细胞膜上通过自组装形成离子及分子通道。 有关系列研究结果已在《美国国家科学院院刊》 (Proc. Nat. Acad. Sci. U.S.A.)、《美国化学会志》（J.Am.Chem.Soc) 和 德国《应用化学》（Angew. Chem.）等科学杂志上发表近50篇论文，被SCI杂志他引500多次。其有关螺旋折叠寡聚物的论文，由于独道的创意，被美国化学会新闻周刊《Chemical & Engineering News》先后报道3次，并作为2002年最重要的化学（纳米科学）进展之一。 1999年获得美国Toledo大学艺术和科学学院优胜奖，2002年获得纽约水牛城州立大学百人联邦奖。1999年以来，历任美国化学会、美国能源部、美国国家自然科学基金(NSF)委员会、美国国立卫生研究院(NIH)生物有机和天然产物部评审委员会、医学化学部评审委员会委员以及香港的大学教育基金委员会评委。2004年和2005年被聘为国家自然科学进步奖海外评审专家以及中国教育部重要人才计划讲座教授。论文发表48. Shape-Persistent Macrocyclic Aromatic Tetrasulfonamides: Molecules with Nanosized Cavities and Their Nanotubular Assemblies in the Solid State， He, L.; An, Y.; Yuan, L. H.; Feng, W.; Li, M. F.; Zhang, D. C.; Yamato, K.; Zheng, C.; Zeng, X. C.; Gong, B. Proc. Natl. Acad. Sci. U. S. A. 2006, in press.47. Engineering Hydrogen Bonded Duplexes. Gong, B.，Polym. Int. 2006, in press (invited contribution)46. Enforced Folding of Unnatural Oligomers: Creating Hollow Helices with Nanosized Pores， Gong, B.; Sanford, A. R.; Ferguson, J. S.，Adv. Polym. Sci.， 2006, in press (invited review article)45. Aromatic Oligoureas: Enforced Folding and Assisted Cyclization，Zhang, A. M.; Han, Y. H.; Yamato, K.; Zeng, X. C.; Gong, B.Org. Lett.，2006, 8, 803-806.44. Molecular Zippers for Preparing Supramolecular and Dynamic Covalent Block Copolymers，Li, M. F.; Yang, X. W.; Ryu, C. R.; Gong, B.，Polym. Preprint ，2005, 46, 1128-1129.43. Synthesis of Crescent Aromatic Oligoamides，Yuan, L. H.; Sanford, A. R.; Feng, W.; Zhang, A. M.; Ferguson, J. S.; Yamato, K.; Zhu, J.; Zeng. H. Q.; Gong, B.，J. Org. Chem. 2005, 70, 10660-10669.42. Macrocyclic Aromatic Tetrasulfonamides with a Stable Cone Conformation，He, H.; An, Y.; Yuan, L. H.; Yamato, K.; Feng, W.; Gerlitz, O.; Zheng, C.; Gong, B.，Chem. Commun. 2005, (30), 3788-3790.41. Cyclic aromatic oligoamides as highly selective receptors for the guanidinium ion，Sanford, A. R.; Yuan, L. H.; Feng, W.; Yamato, K.; Flowers, R. A.; Gong, B.，Chem. Commun. 2005, (37), 4720-4722.40. Stability of a New Class of Unnatural Hydrogen-Bonded Molecular Duplexes, A Computational Study，Li, S. M.; Gong, B.; Guo, H.，Chem. Phys. Lett. 2005, 410, 264-268.39. Template-Assisted Cross Olefin Metathesis，Yang, X. W.; Gong, B.，Angew. Chem., Int. Ed. 2005, 44, 1352-1356.38. Preparation of Oligoamide-Ended Poly(ethylene glycol) and Hydrogen-Bonding-Assisted Formation of Aggregates and Nanoscale Fibers，Hua, F. J.; Yang, X. W.; Gong, B.; Ruckenstein, E.， J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 1119-1128.37. Helical Aromatic Oligoamides: Reliable, Readily Predictable Folding from the Combination of Rigidified Structural Motifs，Yuan, L. H.; Zeng, H. Q.; Yamato, K.; Sanford, A. R.; Feng, W.; Atreya, H.; Sukumaran, D. K.; Szyperski, T.; Gong, B.，J. Am. Chem. Soc. 2004, 126, 16528-16537.36. Supramolecular AB Diblock Copolymers，Yang, X. W.; Hua, F. J.; Yamato, K.; Ruckenstein, E.; Gong, B.; Kim, W.; Ryu, C. Y.，Angew. Chem., Intl Ed. 2004, 43, 6471-6474.35. Highly Efficient, One-Step Macrocyclizations Assisted by Backbone-Preorganization， Yuan, L. H.; Feng, W.; Yamato, K.; Sanford, A. R.; Xu, D. G.; Guo, H.; Gong, B.，J. Am. Chem. Soc. 2004, 126, 11120-11121.34. Well-Defined Secondary Structures: Information-Storing Molecular Duplexes and Helical Foldamers Based on Unnatural Peptide Backbones，Sanford, A.; Yamato, K.; Yang, X. W.; Yuan, L. H.; Han, Y. H.; Gong, B.，Eur. J. Biochem. 2004, 271, 1416-1425.33. Backbone-Rigidified Oligo(m-phenylene ethynylenes)，Yang, X. W.; Yuan, L. H.; Yamato, K.; Brown, A. L.; Feng, W.; Furukawa, M.; Zeng, X. C.; Gong, B.，J. Am. Chem. Soc. 2004, 126, 3148-3162.32. The Evolution of Helical Foldamers，Sanford, A.; Gong, B. Curr. Org. Chem. 2003, 7, 1649-1659.31. Duplex Foldamers from Assembly-Induced Folding，Yang, X. W.; Martinovic, S.; Smith, R. D.; Gong, B. J. Am. Chem. Soc. 2003, 125, 9932-9933.30. An Extremely Stable, Self-Complementary Hydrogen-Bonded Duplex，Zeng, H. Q.; Yang, X. W.; Brown, A. L.; Martinovic, S.; Smith, R. D.; Gong, B.，Chem. Commun. 2003, 1556-155729. A New Strategy for Folding Oligo(m-phenylene ethynylenes)，Yang, X. W.; Brown, A. L.; Furukawa, M.; Li, S.; Gardinier, W. E.; Bukowski, E. J.; Bright, F. V.; Zheng, C.; Zeng, X. C.; Gong. B.，Chem. Commun. 2003, 56-57.28. Creating Nanocavities of Tunable Sizes: Hollow Helices，Gong, B.*; Zeng, H. Q.; Zhu, J. et al., Proc. Natl. Acad. Sci. U. S. A. 2002, 99, 11583-11588. (Featured in Chem. & Eng. News in the issues of September 26, 2002 and December 16, 2002 as one of Chemistry Highlights of 2002)27. Enforced Folding by Localized Intramolecular Hydrogen Bonds: Hollow Helices with Tunable Cavity Size，Gong, B. Acta Cryst. 2002, A58, C226.26. A Non-Covalent Approach to Anti-Parallel Sheet Formation，Zeng, H. Q.; Yang, X. W.; Flowers, II, R. A.; Gong, B. J. Am. Chem. Soc. 2002, 124, 2903-2910.25. Crescent Oligoamides: From Acyclic “Macrocycles” to Folding Nanotubes， Gong, B.* Chem. Eur. J. 2001, 7, 4336-4342.24. Stable Three-Center Hydrogen Bonding in a Partially Rigidified Structure，Parra, R. D.; Zeng, H. Q.; Zhu, J.; Zheng, C.; Zeng, X. C.; Gong, B.，Chem. Eur. J. 2001, 7, 4352-4357.23. Energetics and Cooperativity in Three-Center Hydrogen-Bonding: 1. Diacetamide-X Dimers, (X=HCN, CH3OH).，Parra, R. D.; Furukawa, M.; Gong, B.; Zeng. X. C.，J. Chem. Phys. 2001, 115, 6030-6035.22. Energetics and Cooperativity in Three-Center Hydrogen-Bonding: 2. Intramolecular Hydrogen Bonding Systems，Parra, R. D.; Gong, B.; Zeng. X. C.*，J. Chem. Phys. 2001, 115, 6036-6041.21. Sequence-Specificity of Hydrogen-Bonded Molecular Duplexes， Zeng, H.; Ickes, H.; Flowers, II, R. A.; Gong, B.，J. Org. Chem. 2001, 66, 3574-3583.20. Specifying Non-Covalent Interactions: Sequence-Specific Assembly of Hydrogen-Bonded Molecular Duplexes，Gong, B.*， Synlett 2001, (5), 582-589.19. Structural analysis of the binding modes of minor groove ligands comprised of disubstituted benzenes. Hawkins, C. A; Watson, C; Yan, Y; Gong, B.; Wemmer, D. E.，Nucleic Acids Res. 2001, 29, 1-718. Two-Dimensional Molecular Layers: Interplay of H-Bonding and van der Waals Interactions in the Self-Assembly of N,N’-Dialkylsulfamides，Gong, B.*; Zheng, C.; Skrzypczak-Jankun, E.; Zhu, J. Org. Lett. 2000, 2, 3273-327517. A New Class of Folding Oligomers: Crescent Oligoamides， Zhu, J.; Parra, R. D.; Zeng, H.; Skrzypczak-Jankun, E.; Zeng, X. C.; Gong, B.，J. Am. Chem. Soc. 2000, 122, 4219-4220.(Featured in the May 1, 2000 issue of Chem. & Eng. News)16. A Highly Stable, Six-Hydrogen Bonded Molecular Duplex， Zeng, H.; Miller, R.; Flowers, R. A.; Gong, B.，J. Am. Chem. Soc. 2000, 122, 2635-264415. Polar Assembly of N,N’-Bis(4-substituted benzyl)sulfamides，Gong, B.; Zheng, C.; Zhu, J.; Zeng, H. J. Am. Chem. Soc. 1999, 121, 9766-976714. A New Approach for the Design of Supramolecular Recognition Units: Hydrogen-Bonded Molecular Duplexes，Gong, B.; Yan, Y.; Zeng, H.; Skrzypczak-Jankunn, E.; Kim, Y. W.; Zhu, J.; Ickes, H.，J. Am. Chem. Soc. 1999, 121, 5607-560813. Structure of N,N’,N’-tris(carboxymethyl)-1,3,5-benzenetricarboxamide trihydrate，Gong, B.; Zheng, C.; Yan, Y.，J. Chem. Crystallogr. 1999, 29(6), 649-65212. Structure of N,N’-bis[3-(aminocarbonyl)propyl]sulfamide，Gong, B.; Zheng, C.; Zhang, J.，J. Chem. Crystallogr. 1999, 29(6), 645-64811. DNA Sequence Recognition by a Novel Series of Minor Groove-Binding Ligands，Fox, K.R.; Yan, Y.; Gong, B.，Anti-Cancer Drug Design 1999, 14, 219-23010. A Robust Two-Dimensional Supramolecular Module: the Sulfamide Moiety as A New Building Block for the Design and Self-Assembly of Molecular Solids.，Gong, B.; Y. Yan.; Zheng, C. J. Am. Chem. Soc. 1998, 120, 11194-111959. A Catalytic Antibody for Hydrolysis of Peptides，Yoon, S. S.; Gong, B.; Schultz, P. G.，J. Korean Chem. Soc. 1998, 42(4), 4628. Photoactivated Prodrug，Wei, Y.; Yan, Y.; Pei, D.; Gong, B. Bioorg. Med. Chem. Lett. 1998, 8(18), 2419-24227. A Convenient Preparation of a Bicyclo[3.3.3]-Undecane Derivative Containing Heteroatoms Through a Rearrangement Step，Tian, J.; Yan, Y.; Gong, B.; Valente, E. J.; Zubkowski, J. D.，Synth. Commun.1998, 28(10), 19076. A New Class of DNA Minor Groove Binders Rivaling the Natural Product Distamycin，Gong, B. and Yan, Y.，Biochem. Biophys. Res. Commun. 1997, 240(3), 5575. Two-Ring DNA Minor Groove Binders Consisting of Readily Available, Di-substituted Benzene Derivatives， Yan, Y.; Liu, M.; Gong, B.，Bioorg. Med. Chem. Lett. 1997, 7, 14694. An Antibody Activated Prodrug，Campbell, D. V.; Gong, B.; Kochersperger, L.M.; Yonkovich, S.; Gallop, M. A.; Schultz, P. G.，J. Am. Chem. Soc. 1994, 116, 21653. Antibody Catalyzed Oxime Formation，Uno, T.; Gong, B.; Schultz, P. G. J. Am. Chem. Soc. 1993, 116, 11452. A Chromogenic Assay for Screening Large Antibody Libraries，Gong, B.; Lesley, A. S. and Schultz, P. G. J. Am. Chem. Soc. 1992, 114, 14861. Regioselective Reduction of Diacids: Aspartic Acid to Homoserine，Gong, B.; Lynn, D. G. J. Org. Chem. 1990, 55(15), 4763专利：“Helices and Nanotubes on Folding Compositions and Methods of Preparation” issued December 17, 2002. US Patent No. 6,495,680 B1
